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Fundamentals of Hemostasis

Author: Carl T. Swithers BSMT (ASCP), CLS (NCA), MBA
Reviewer: Loretta Moffatt, MT(ASCP),MHA

This course identifies and discusses the aspects of primary and secondary hemostasis. The extrinsic, intrinsic, and common pathways that are part of the coagulation cascade are defined, and the various laboratory tests that are used to evaluate hemostasis are discussed.

Continuing Education (CE) Credits

P.A.C.E. Contact Hours: 1 hour(s)
Florida CE: General (Hematology): 1 hour(s)

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Fundamentals of Hemostasis Objectives

Identify the factors that influence the effectiveness of HEMOSTATIC processes.
Describe the mechanisms that are involved in the arrest of BLOOD flow from a damaged vessel.
Identify key aspects associated with primary and secondary HEMOSTASIS.
Explain the role of various COAGULATION components in HEMOSTATIC processes.
Define the extrinsic, intrinsic, and common pathways that are part of the COAGULATION cascade, IDENTIFYING the COAGULATION factors that are associated with each pathway.
Describe the function of various LABORATORY tests in evaluating HEMOSTASIS.
Identify common COAGULATION disorders, their SYMPTOMOLOGY, and subsequent TREATMENT.
Explain the role of the PROTHROMBIN time and activated partial THROMBOPLASTIN time in monitoring ANTICOAGULATION therapy.

Fundamentals of Hemostasis Outline

An Introduction to the Fundamentals of COAGULATION

An Introduction to the Fundamentals of COAGULATION
An Introduction to the Fundamentals of COAGULATION
An Introduction to the Fundamentals of COAGULATION
An Introduction to the Fundamentals of COAGULATION
An Introduction to the Fundamentals of COAGULATION
From what you have learned thus far, which of the following would not impact the effectiveness of HEMOSTATIC processes?

Introduction to Primary HEMOSTASIS

Introduction to HEMOSTATIC Mechanisms
Introduction to Primary HEMOSTASIS
Primary HEMOSTASIS � The Vascular SySTEM
Primary HEMOSTASIS � The Vascular SySTEM
Primary HEMOSTASIS � The Vascular SySTEM
Primary HEMOSTASIS � The Vascular SySTEM & PLATELET Involvement
Primary HEMOSTASIS � The Vascular SySTEM & PLATELET Involvement
All of the following processes occur during primary HEMOSTASIS except:
Primary HEMOSTASIS � Characteristics of the PLATELET
Primary HEMOSTASIS � Characteristics of the PLATELET
Primary HEMOSTASIS � PLATELET Function
Primary HEMOSTASIS � PLATELET KINETICS
All of the following are activities associated with PLATELETS except:
Summary of Primary HEMOSTASIS

Overview of Secondary HEMOSTASIS

Overview of Secondary HEMOSTASIS
Secondary HEMOSTASIS � FIBRIN Formation via the COAGULATION Cascade
Secondary HEMOSTASIS � The COAGULATION Cascade
The ultimate goal of secondary HEMOSTASIS is:
A Snapshot of the Entire COAGULATION Cascade
Secondary HEMOSTASIS � The Extrinsic Pathway
Secondary HEMOSTASIS � The Extrinsic Pathway
Secondary HEMOSTASIS � The Extrinsic Pathway
Secondary HEMOSTASIS � The Intrinsic Pathway
Secondary HEMOSTASIS � The Intrinsic Pathway
Secondary HEMOSTASIS � The Intrinsic Pathway
Secondary HEMOSTASIS � The Intrinsic Pathway
Secondary HEMOSTASIS � The Intrinsic Pathway
Which of the following statements is incorrect?
Secondary HEMOSTASIS � The Common Pathway
Secondary HEMOSTASIS � The Common Pathway
Secondary HEMOSTASIS � The Common Pathway
Secondary HEMOSTASIS - Factor Characteristics

The FIBRINOLYTIC SySTEM

The FIBRINOLYTIC SySTEM
The FIBRINOLYTIC SySTEM

LABORATORY Tests of HEMOSTATIC Function

LABORATORY Tests of HEMOSTATIC Function
Collecting BLOOD Specimens for COAGULATION Testing
LABORATORY Tests of HEMOSTATIC Function
LABORATORY Tests of HEMOSTATIC Function � PROTHROMBIN Time
LABORATORY Tests of HEMOSTATIC Function � PROTHROMBIN Time
LABORATORY Tests of HEMOSTATIC Function - APTT
Which of the following statements is incorrect?
Tests of HEMOSTATIC Function � FIBRINOGEN ASSAY
FIBRIN/FIBRINOGEN Degradation Products and D-DIMERS
Tests of HEMOSTATIC Function - PLATELET Function ASSAY
Tests of HEMOSTATIC Function - Mixing Studies
Tests of HEMOSTATIC Function - Factor ASSAYS
Which of the following statements is incorrect?

COAGULATION Disorders

COAGULATION Disorders
COAGULATION Disorders - Inherited
COAGULATION Disorders - Inherited
COAGULATION Disorders - Inherited
COAGULATION Disorders - Acquired
COAGULATION Disorders - Acquired
COAGULATION Disorders - PLATELET Disorders
COAGULATION Disorders and LIVER DISEASE
Which of the following statements regarding COAGULATION disorders is incorrect?

ANTICOAGULATION Therapy

ANTICOAGULATION Therapy
ANTICOAGULATION Therapy - HEPARIN Therapy
ANTICOAGULATION Therapy - Oral ANTICOAGULANT Therapy

Fundamentals of Hemostasis Keywords

Click on a term below to see its use in this Fundamentals of Hemostasis course and other available MediaLab courses.

coagulation (44 occurances)
hemostasis (34 occurances)
platelet (33 occurances)
hemostatic (28 occurances)
blood (17 occurances)
fibrin (15 occurances)
anticoagulant (13 occurances)
clotting (13 occurances)
chemical (12 occurances)
plasma (10 occurances)
vasculature (10 occurances)
inhibitor (9 occurances)
laboratory (8 occurances)
disease (8 occurances)
fibrinogen (8 occurances)
assay (8 occurances)
deficiency (8 occurances)
treatment (8 occurances)
thrombin (8 occurances)
prothrombin (7 occurances)
clinical (7 occurances)
aggregation (7 occurances)
adhesion (7 occurances)
fibrinolysis (7 occurances)
heparin (6 occurances)
fibrin clot (6 occurances)
willebrand (6 occurances)
vitamin (5 occurances)
vasoconstriction (5 occurances)
hemophilia (5 occurances)
liver (5 occurances)
body (5 occurances)
circulating (4 occurances)
calcium (4 occurances)
adp (4 occurances)
anticoagulation (4 occurances)
catalyzes (4 occurances)
clinician (4 occurances)
diagnostic (4 occurances)
drug (4 occurances)
intravascular (4 occurances)
precursor (4 occurances)
fibrinolytic (4 occurances)
thromboplastin (4 occurances)
thrombosis (4 occurances)
warfarin (4 occurances)
symptom (4 occurances)
subendothelial (3 occurances)
serotonin (3 occurances)
venous (3 occurances)
granules (3 occurances)
hageman (3 occurances)
hmwk (3 occurances)
dissolution (3 occurances)
dosage (3 occurances)
ionized (3 occurances)
cryoprecipitate (3 occurances)
d-dimer (3 occurances)
coumarin (3 occurances)
clinical laboratory (3 occurances)
abnormal (3 occurances)
biochemical (3 occurances)
assessment (3 occurances)
assayed (2 occurances)
bone marrow (2 occurances)
bernard-soulier (2 occurances)
citrate (2 occurances)
abnormalities (2 occurances)
activator (2 occurances)
aids (2 occurances)
amp (2 occurances)
antagonist (2 occurances)
covalent (2 occurances)
dysfunction (2 occurances)
diagnosis (2 occurances)
lysis (2 occurances)
macrophages (2 occurances)
intravenously (2 occurances)
hemorrhagic (2 occurances)
ixa (2 occurances)
megakaryocyte (2 occurances)
metabolic (2 occurances)
monomer (2 occurances)
epithelial (2 occurances)
equilibrium (2 occurances)
exposure (2 occurances)
fdp (2 occurances)
fibrinogenolysis (2 occurances)
fletcher (2 occurances)
homeostasis (2 occurances)
vein (2 occurances)
trauma (2 occurances)
tubing (2 occurances)
waterfall (2 occurances)
vwf (2 occurances)
plasmin (2 occurances)
plasminogen (2 occurances)
sodium (2 occurances)
spiny (2 occurances)
ratio (2 occurances)
nomenclature (2 occurances)
subendothelium (2 occurances)
sensitivity (2 occurances)
stuart-prower (2 occurances)
stem (2 occurances)
syndrome (2 occurances)
tfpi (2 occurances)
thromboembolism (2 occurances)

Fundamentals of Hemostasis

Author: Carl T. Swithers BSMT (ASCP), CLS (NCA), MBA Reviewer: Loretta Moffatt, MT(ASCP),MHA

Author: Carl T. Swithers BSMT (ASCP), CLS (NCA), MBA
Reviewer: Loretta Moffatt, MT(ASCP),MHA